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Urinary Protein — Calculated Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

A calculated laboratory measurement estimates the concentration of protein in urine and may be used to help assess kidney function.

Quick summary

["An elevated urine protein result can be a sign of kidney stress or damage, but temporary factors and other health conditions can also affect it."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
72790-9
Short code
PPAA Ur Cfm-mCnc
Synonyms
PPAA Ur Cfm-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
confirm
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test estimates how much protein is present in a urine sample. Protein is normally present in only small amounts in urine, so a higher concentration can sometimes indicate that the kidneys are allowing more protein to pass into the urine.

Why might I need this test?

Urine protein may be checked during routine kidney screening or when there is concern about kidney disease, diabetes, high blood pressure, or swelling. It can also be used to monitor people with known kidney conditions.

How is the test performed?

A urine specimen is collected and analyzed in the laboratory. Because this result may be calculated from other urine measurements, the laboratory may combine it with related test results before reporting it.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional. A first-morning or timed urine collection may be requested, and vigorous exercise shortly before collection can temporarily increase urine protein. Tell your clinician about medicines, supplements, and urinary symptoms.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine protein

Frequently asked questions

Does a small amount of protein in urine always mean something is wrong?
No. Small amounts can be found temporarily, especially after exercise or during an infection. Persistent or clearly increased urine protein is more likely to be clinically important.
What conditions commonly cause elevated urine protein?
Common causes include diabetes, high blood pressure, kidney inflammation, and other forms of kidney disease. Fever, infection, exercise, and some medicines can also cause a temporary increase.
Is this the same as a urine protein-to-creatinine ratio?
Not necessarily. A urine protein-to-creatinine ratio is a specific calculated comparison, while this result reports a calculated protein concentration. Ask the laboratory or your clinician which measurement appears on your report.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy