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Prostate-Specific Antigen (PSA), Urine — Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

Measures the amount of prostate-specific antigen in urine. Unlike blood PSA, urine PSA is not commonly used by itself for prostate cancer screening.

Quick summary

["This test measures PSA in urine, but a blood PSA test is the standard way to evaluate prostate health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33507-5
Short code
PPAA Ur-mCnc
Synonyms
PPAA Ur-mCnc
Category
liver
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Prostate-specific antigen, or PSA, is a protein made by prostate cells. This test measures the concentration of PSA in a urine sample.

Why might I need this test?

Urine PSA may be ordered in selected situations to assess prostate-related activity. It is not generally used by itself to screen for prostate cancer, and results are usually interpreted alongside other findings.

How is the test performed?

A urine sample is collected and tested in the laboratory to determine the amount of PSA present. The laboratory may report the result as a mass concentration.

How do I prepare for the test?

Follow the collection instructions provided by your healthcare professional, which may include a clean-catch urine sample. Tell your clinician if you recently had a prostate examination, urinary procedure, infection, or symptoms affecting urination.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated urine PSA result may occur with prostate enlargement, inflammation, infection, recent prostate procedures, or other prostate conditions. It does not by itself establish whether prostate cancer is present. Your clinician will consider symptoms, examination findings, other laboratory tests, and whether a blood PSA test is appropriate.

Short name

Urine PSA

Frequently asked questions

Is urine PSA the same as a routine blood PSA test?
No. They use the same type of biomarker but measure it in different samples. Blood PSA is the more commonly used test for evaluating prostate health.
Does an elevated urine PSA result mean I have prostate cancer?
No. An elevated result can have several causes and does not diagnose cancer by itself. Follow-up may include a clinical review, repeat testing, or blood PSA testing.
Can urinary symptoms or recent procedures affect the result?
Yes. Urinary infection, inflammation, prostate procedures, and other temporary changes may affect PSA levels. Inform your clinician about recent urinary or prostate-related events.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy