Plasma or Serum Protein Electrophoresis (Qualitative)
This test measures the distribution of different protein types in your blood, often used to check for conditions like multiple myeloma, infections, or liver/kidney disorders.
["Helps identify abnormal protein patterns that may signal underlying health concerns."]
Key facts at a glance
- LOINC
- 17443-3
- Short code
- PPA Ur-mCnc
- Synonyms
- PPA Ur-mCnc
- Category
- chemistry
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What Proteins Does This Test Measure?
Electrophoresis separates blood proteins into fractions based on size and charge. Key components include albumin (smallest, most abundant), globulins (antibodies, immune proteins), and other fractions like alpha, beta, and gamma globulins. Abnormal patterns may indicate conditions like multiple myeloma, infections, or liver disease.
Why Might You Need This Test?
Your doctor may order this test if you have symptoms like unexplained weight loss, fatigue, frequent infections, or swelling. It’s also used to monitor conditions like kidney disease, liver disease, or certain cancers.
Common Conditions Detected
Abnormal results may reveal conditions such as multiple myeloma (bone marrow cancer), monoclonal gammopathy (excess antibodies), infections (e.g., chronic hepatitis), or liver/kidney dysfunction. Low albumin could signal malnutrition or liver issues.
Sample Preparation and Testing
A blood sample is drawn, and plasma or serum is separated. The sample is placed in an electric field, causing proteins to migrate toward the opposite charge. A gel or paper strip captures the separation, creating a visual pattern for analysis.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: This test is critical for diagnosing and managing conditions affecting protein balance in the blood. For example, elevated gamma globulins may indicate immune disorders, while unusual patterns could signal hidden cancers or metabolic issues. Early detection improves treatment planning.
Short name
Protein Electrophoresis (Qual)
Frequently asked questions
What does a ‘qualitative’ result mean?
How long does it take to get results?
Can I fast before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy