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Protein Electrophoresis (Serum) with Bromocresol Green (BCG) Dye Shift

Published: August 9, 2026Updated: August 16, 2026

This test measures protein fractions in your blood using electrophoresis and a dye called bromocresol green. It helps identify patterns of protein distribution that may indicate conditions affecting protein synthesis, breakdown, or transport.

Quick summary

["This test helps doctors diagnose and monitor conditions like liver disease, kidney disease, or protein disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40557-1
Short code
PR Ag Tiss Ql ImStn
Synonyms
PR Ag Tiss Ql ImStn
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Electrophoresis separates proteins in your blood based on size and charge, creating bands that correspond to different protein types. Bromocresol green binds to proteins differently depending on their concentration, allowing for precise measurement of key protein fractions, including albumin and globulins.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like swelling, fatigue, or unexplained weight changes, or if they suspect conditions like cirrhosis, multiple myeloma, or other protein-related disorders.

Common Conditions Monitored

This test helps track protein imbalances in diseases like chronic liver disease, kidney disease, or certain cancers. It can also reveal subtle shifts in protein levels that might not be detected by simpler tests.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum, where proteins are analyzed using electrophoresis and the BCG dye method.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

BCG Protein Electrophoresis

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 24 to 48 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
What do abnormal results mean?
Abnormal results may indicate an excess or deficiency of specific proteins, which can signal conditions like liver disease (e.g., low albumin), immune disorders (e.g., elevated globulins), or metabolic issues. Your doctor will interpret results in the context of your symptoms and medical history.
Can I eat or drink anything before this test?
No special preparation is needed for this test. However, avoid alcohol for 24 hours before your blood draw, as it may affect protein levels.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy