Pravastatin-Induced Platelet IgM Antibody, Serum/Plasma — Qualitative
Detects IgM antibodies that bind to platelets in the presence of pravastatin, which may support evaluation for drug-induced immune thrombocytopenia.
["A positive result can indicate a pravastatin-related immune reaction affecting platelets, but it must be interpreted with your symptoms and medication history."]
Key facts at a glance
- LOINC
- 73198-4
- Short code
- Pravastatin ind plt IgM SerPl Ql FC
- Synonyms
- Pravastatin ind plt IgM SerPl Ql FC
- Category
- liver
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 10
- Ref high
- 40
- Critical range
- — – 500 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- flow-cytometry
- CPT
- 84484
- SNOMED
- 302774002
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This blood test looks for IgM antibodies directed against platelets when pravastatin is present. These antibodies are part of an immune reaction that may reduce circulating platelets.
Why might I need this test?
Your clinician may order it if you developed a low platelet count, unusual bruising, nosebleeds, or other bleeding signs after taking pravastatin. It may also be considered when another medication-related immune platelet disorder is suspected.
How is the test performed?
A serum or plasma sample is collected from a blood draw. A laboratory uses a specialized antibody-testing method to determine whether the sample contains platelet-reactive IgM with or without pravastatin.
How do I prepare for the test?
Fasting is generally not required. Tell the laboratory and your clinician which medicines you take, when pravastatin was started or stopped, and whether bleeding or bruising symptoms began after starting it. Do not stop any medication without medical advice.
Reference range
Adult: 10-40 U/LN/A
No special preparation required. Avoid fatty meals before the test if possible.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
A positive result may support pravastatin-induced immune thrombocytopenia, particularly when low platelets and bleeding symptoms developed during treatment. A negative result does not completely exclude the condition, and results must be interpreted alongside the medication timeline, blood count, symptoms, and other laboratory findings.
Short name
Pravastatin-induced platelet IgM antibody test
Frequently asked questions
What does a positive result mean?
Does the test show that my platelet count is low?
Should I stop taking pravastatin if the result is positive?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy