Serum albumin and alpha-1 antitrypsin electrophoresis profile
This test measures the distribution of albumin and alpha-1 antitrypsin proteins in your blood using electrophoresis, a technique that separates proteins based on size and charge.
["Helps assess liver function, protein balance, and potential genetic disorders affecting these proteins."]
Key facts at a glance
- LOINC
- 72579-6
- Short code
- Prealb MFr.DF CSF Elph
- Synonyms
- Prealb MFr.DF CSF Elph
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Ref low
- 7.35
- Ref high
- 7.45
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test to evaluate liver disease, genetic conditions (like alpha-1 antitrypsin deficiency), or conditions affecting protein metabolism. It can also help monitor protein levels in chronic kidney disease or other conditions that alter blood protein composition.
What to Expect Before the Test
No special preparation is needed. You’ll provide a blood sample drawn from a vein, typically in a clinic or lab. The test involves minimal discomfort and takes about 5 minutes.
What the Test Results Mean
Electrophoresis separates proteins into bands, showing relative amounts of albumin and alpha-1 antitrypsin. Abnormal patterns may indicate liver disease, genetic disorders, or other conditions affecting protein synthesis or breakdown.
Common Conditions Monitored
This test helps diagnose or monitor conditions like chronic obstructive pulmonary disease (COPD), cirrhosis, or hereditary protein disorders. It may also guide treatment decisions for liver or kidney disease.
Reference range
NCBI: pH 7.35-7.45N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical significance: Abnormal electrophoresis results can signal underlying issues such as liver fibrosis, genetic mutations affecting alpha-1 antitrypsin, or protein disorders. Low albumin may indicate malnutrition or kidney disease, while altered alpha-1 antitrypsin patterns can point to COPD or hereditary deficiencies.
Short name
Albumin & Alpha-1 Antitrypsin Electrophoresis
Frequently asked questions
What does an abnormal electrophoresis result mean?
How long does it take to get results?
Can diet affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy