Prenatal Genetic Panel (Prenatal Sequence PhenX)

What Does This Test Measure?

The test evaluates a selection of genes linked to common genetic conditions, including those affecting organ development, metabolism, and structural integrity. It may include checks for chromosomal abnormalities (e.g., Down syndrome) and specific single-gene disorders (e.g., cystic fibrosis, spinal muscular atrophy). Some tests also assess structural anomalies like neural tube defects.

Why Is This Test Ordered?

Your healthcare provider may recommend this test if you’re pregnant, especially if you’re over 35, have a family history of genetic disorders, or have had previous pregnancy complications. It can also be part of a routine prenatal screening if you’re at higher risk.

Sample Collection and Preparation

A blood sample is typically collected from you during a routine prenatal visit. In some cases, saliva or other fluids may be used. The sample is sent to a lab for genetic analysis. You’ll receive instructions on how to prepare, often including fasting or avoiding certain medications.

Test Results and Follow-Up

Results are usually available within 1–2 weeks. If your results show an increased risk for certain conditions, your healthcare provider will discuss next steps, which may include additional testing or counseling. Normal results mean no obvious genetic risks were detected in this test.