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Pregnancy-specific glycoprotein (PSG) mass concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of pregnancy-specific glycoproteins in your blood. These proteins are produced by the placenta and can help track early pregnancy progression.

Quick summary

["PSGs help monitor early pregnancy health and detect potential issues early."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2831-6
Short code
Preg Sp Prot1 Ser-mCnc
Synonyms
Preg Sp Prot1 Ser-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why is this test done?

Your healthcare provider may order this test during early pregnancy to assess placental development, detect early pregnancy complications, or evaluate the effectiveness of fertility treatments. It’s often used alongside other tests like beta-hCG to monitor progress.

What does the result mean?

Higher than expected levels may indicate normal placental growth, while lower levels could signal early pregnancy loss, ectopic pregnancy, or other concerns. Your results will be interpreted in the context of your clinical history and other tests.

How is the sample collected?

A blood sample is drawn from a vein, usually in your arm. You may feel a slight pinch, but it shouldn’t cause significant discomfort. The sample is sent to the lab for analysis.

What should I expect before or after the test?

No special preparation is needed. Avoid alcohol or certain medications for 24 hours before the test if instructed by your provider. After the draw, you can resume normal activities, though you may experience mild bruising or soreness at the site.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: PSG levels are elevated during pregnancy due to placental production. Abnormalities may signal placental insufficiency, miscarriage risk, or other pregnancy-related complications. This test is particularly useful in early pregnancy when other markers like hCG may be less reliable.

Short name

PSG Level

Frequently asked questions

How soon will I get my results?
Results are typically available within 1–3 business days, depending on lab processing times. Your healthcare provider will discuss them with you during your follow-up visit.
What if my results are outside the expected range?
Your provider will review the results with you and may recommend additional testing or monitoring, such as ultrasounds or further bloodwork, to investigate the cause of any deviations.
Can I fast before this test?
No fasting is required for this test. However, always follow your provider’s specific instructions for any other tests you may have scheduled on the same day.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy