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Probenecid Concentration (24-Hour Urine)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of probenecid, a medication, in your urine over 24 hours to assess how well your kidneys are removing it from your body.

Quick summary

["This test helps evaluate kidney function and drug clearance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4407-3
Short code
Primidone Dose
Synonyms
Primidone Dose
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking probenecid, a drug used to treat certain kidney conditions like gout or to prevent kidney stones. It helps check how your kidneys are processing the medication and whether it’s working as intended.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period. Typically, you’ll start by emptying your bladder completely at the beginning of the test and then collect every bit of urine for the next 24 hours. Store the urine in a cool, dark container until you return it to the lab.

During the Test Process

No special preparation is needed beyond collecting urine as directed. The lab will analyze the sample to determine the concentration of probenecid.

Possible Results and Interpretation

Results are compared to your baseline or clinical picture, not to a standard range. Your doctor will interpret the results in relation to your health and medication use.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Probenecid levels help monitor kidney function and drug effectiveness. High levels might indicate poor kidney function or improper dosing, while normal levels confirm the medication is being processed as expected. This test is critical for managing conditions like gout or preventing kidney stones.

Short name

Probenecid in Urine

Frequently asked questions

What does a probenecid urine test measure?
This test measures the total amount of probenecid, a medication, excreted in your urine over a 24-hour period.
How long does it take to get results from this test?
Results are typically available within 1–3 business days, depending on lab processing times.
Can I drink alcohol before this test?
Alcohol is generally not restricted unless your doctor specifies otherwise, as it does not typically interfere with probenecid measurement in urine.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy