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Indomethacin Plasma Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of indomethacin, a nonsteroidal anti-inflammatory drug, in your blood plasma. It helps monitor drug levels to ensure safe and effective treatment.

Quick summary

["This test helps doctors check if your indomethacin dose is working properly and at safe levels."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
73194-3
Short code
Primidone ind plt IgM SerPl Ql FC
Synonyms
Primidone ind plt IgM SerPl Ql FC
Category
hematology
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
flow-cytometry
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking indomethacin (a medication used to reduce pain, swelling, or fever) and want to ensure the right amount is in your blood. It’s especially important for long-term use or in people with certain kidney or liver conditions.

What to Expect Before the Test

No special preparation is needed. You’ll have a small needle inserted into your arm or vein to draw a blood sample. The process is quick and usually painless. If you’re on blood thinners or have a history of bleeding issues, let your provider know before the test.

What the Results Mean

Results show the concentration of indomethacin in your blood plasma. While reference ranges vary by lab, lower-than-expected levels may mean your medication isn’t working as intended, while dangerously high levels could indicate side effects or improper dosing.

Common Uses and Considerations

Indomethacin is often used for conditions like arthritis, gout, or to prevent certain types of heart valve problems. Your provider may adjust your dose based on these results, especially if you have kidney problems or take other medications that interact with indomethacin.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Indomethacin Level

Frequently asked questions

How often should I get this test if I’m taking indomethacin long-term?
Your provider will determine the frequency based on your treatment plan, health status, and other medications. Typically, it’s done periodically (e.g., every few weeks or months) to monitor levels and avoid side effects like stomach irritation or kidney strain.
Can I eat or drink before this test?
You can eat and drink normally unless instructed otherwise by your provider. Indomethacin levels are measured in plasma, so fasting isn’t required.
What are the most common side effects of indomethacin that this test helps prevent?
This test helps track whether your dose is too high, which could lead to side effects like stomach ulcers, dizziness, or kidney problems. It’s also useful for ensuring adequate levels for pain relief or preventing complications like blood clots.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy