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Protein Electrophoresis (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood, including albumin and globulins, which help your body function properly. It can help identify conditions affecting protein balance.

Quick summary

["This test helps doctors check for protein disorders or conditions like kidney disease, infections, or autoimmune disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
71502-9
Short code
PROFITSTATUS
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
esrd
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Does This Test Measure?

Protein electrophoresis separates blood proteins into fractions based on size and electrical charge. This helps identify abnormal protein patterns that may indicate underlying health issues.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like unexplained weight loss, fatigue, swelling, or if they suspect conditions like multiple myeloma, liver disease, or chronic infections.

Common Uses and Indications

This test is often used to diagnose or monitor conditions such as kidney disease, autoimmune disorders, infections, or to check for protein abnormalities in the bloodstream.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate the serum for testing. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Serum Protein Electrophoresis

Frequently asked questions

Protein electrophoresis can reveal abnormal protein levels that may signal conditions like multiple myeloma (cancer of plasma cells), liver disease, or chronic kidney disease. It may also help detect inflammatory conditions or infections.
How long does it take to get results from this test?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your doctor will discuss the findings with you during your follow-up visit.
What does it mean if my protein electrophoresis shows abnormal results?
Abnormal results may indicate conditions like protein abnormalities, kidney disease, liver problems, or certain cancers. Your doctor will interpret the results in the context of your medical history and symptoms to guide further testing or treatment.
Check with your doctor or lab technician about fasting requirements, as some labs may require fasting for accurate results. Generally, you can eat and drink normally unless instructed otherwise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy