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Progesterone, Serum (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone important for reproductive health, in your blood serum.

Quick summary

["Progesterone levels help track fertility, pregnancy, and hormone balance."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47183-9
Short code
Progest 15M p chal SerPl-sCnc
Synonyms
Progest 15M p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate reproductive health, diagnose hormonal imbalances, assess fertility, or monitor conditions like endometriosis, polycystic ovary syndrome (PCOS), or pregnancy-related issues. It can also help guide treatment for hormone-related disorders.

What Does the Test Measure?

Progesterone is a steroid hormone produced primarily by the ovaries, placenta, and adrenal glands. It plays a key role in regulating the menstrual cycle, preparing the uterus for pregnancy, and maintaining early pregnancy. Levels fluctuate throughout the menstrual cycle and pregnancy.

Sample Collection and Preparation

A blood sample is drawn from a vein, usually in your arm, by a healthcare professional. The blood is then processed to separate serum (the liquid part after clotting) for testing. This test is typically performed on serum.

What Are Common Uses?

Common reasons for testing include: tracking ovulation, diagnosing infertility, assessing hormonal imbalances, evaluating conditions like luteal phase deficiency, monitoring pregnancy, or checking for signs of hormonal tumors.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Progesterone

Frequently asked questions

Progesterone levels can indicate whether ovulation occurred (high levels suggest ovulation), help diagnose conditions like PCOS or endometriosis, or assess risks of miscarriage or preterm labor. Abnormal levels may also signal thyroid disorders, adrenal issues, or other endocrine problems.
How soon after my period can I get this test?
Ideal timing varies by cycle phase. Typically, tests are done mid-luteal phase (around day 21–23 of a 28-day cycle) or during pregnancy. Your provider will specify the best window for your situation.
What do my results mean?
Results are interpreted by your healthcare provider based on your cycle phase, medical history, and symptoms. Low levels may suggest ovulation issues or hormonal deficiencies, while high levels could indicate pregnancy or certain tumors. No absolute reference ranges are provided here; your provider will guide interpretation.
No special preparations are usually needed, but avoid alcohol for 24 hours before testing. If you’re taking hormonal medications (like birth control), discuss this with your provider, as it may affect results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy