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Progesterone, Serum (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced mainly by the ovaries, in your blood. Progesterone plays a key role in regulating the menstrual cycle and supporting pregnancy.

Quick summary

["Progesterone levels help diagnose fertility issues, monitor ovulation, or check hormone imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47187-0
Short code
Progest 45M p chal SerPl-sCnc
Synonyms
Progest 45M p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
4.5
Ref high
12
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84436
SNOMED
302345006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test if you're experiencing irregular menstrual periods, trouble getting pregnant, symptoms of hormonal imbalances, or if you’re undergoing fertility treatments. It can also help assess conditions like polycystic ovary syndrome (PCOS) or evaluate ovarian function.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Wear a comfortable shirt for easy access to your arm.

What Happens During the Test?

A healthcare professional will insert a small needle into a vein in your arm to collect a blood sample. You may feel a slight pinch, but it typically only takes a few minutes. The blood is then sent to a lab for analysis.

What Does the Test Result Mean?

Results are compared to a general reference range to help identify whether your hormone levels are within normal limits or if further evaluation is needed. Your provider will discuss the results with you in the context of your health.

Reference range

Adult: 4.5-12.0 μg/dLN/A

Specimen: serum

Take your thyroid medication after the blood draw if applicable. No fasting required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Progesterone levels can indicate ovulation timing, help diagnose conditions like luteal phase deficiency (which may affect fertility), or signal hormonal disorders. Low levels might suggest issues with ovulation or ovarian function, while high levels could be seen in pregnancy or certain tumors. Always interpret results with your healthcare provider’s guidance.

Short name

Serum Progesterone

Frequently asked questions

How often should I get this test?
The frequency depends on your medical needs. For fertility or menstrual cycle monitoring, it might be done monthly or during specific phases of your cycle. Your provider will determine the best schedule for you.
What are common reasons for abnormal results?
Abnormal results could be due to conditions like polycystic ovary syndrome (PCOS), ovarian cysts, or hormonal imbalances. They may also reflect pregnancy, thyroid disorders, or certain medications. Your provider will investigate further if needed.
Can lifestyle changes affect progesterone levels?
Yes, factors like stress, poor sleep, excessive exercise, or certain medications (e.g., birth control) can influence hormone levels. Maintaining a balanced diet, managing stress, and staying hydrated may support overall hormonal health.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy