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Serum/plasma progesterone concentration (first-void urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone present in your first-morning urine sample. Progesterone is a hormone important in reproductive health, particularly during pregnancy.

Quick summary

["Urine progesterone helps track hormone levels for fertility, pregnancy, or hormonal imbalance evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63883-3
Short code
Progesterone age first CTS
Synonyms
Progesterone age first CTS
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.1
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
california-teachers-study
CPT
84144
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test to assess hormone levels in conditions like infertility, menstrual cycle irregularities, or pregnancy. It can also help monitor hormone therapy or evaluate ovarian function.

What to Expect Before the Test

You’ll collect your first-morning urine sample in a clean container. Avoid using toilet paper or sanitary products that might contaminate the sample. Bring the sample to your lab within 2 hours for accurate results.

What to Expect During the Test

No special preparation is needed beyond collecting the urine sample. The lab will analyze the urine for progesterone levels using a sensitive immunoassay method.

What the Results Mean

Results are typically reported in arbitrary units concentration (ucnc). Higher levels may indicate pregnancy or certain reproductive conditions, while lower levels could suggest hormonal imbalances or early pregnancy.

Reference range

Follicular: 0.1-1.5 ng/mL; Luteal: 2-20 ng/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Progesterone

Frequently asked questions

How is this test used in clinical practice?
Urine progesterone testing is often used to diagnose or monitor conditions like luteal phase deficiency, polycystic ovary syndrome (PCOS), or to confirm pregnancy early. It can also guide treatment decisions for fertility issues or hormonal replacement therapy.
What do abnormal results indicate?
Abnormally low progesterone levels may suggest issues with ovulation, hormonal imbalances, or early pregnancy loss. Abnormally high levels could indicate pregnancy or rare conditions like ovarian tumors. Always discuss results with your provider.
How often is this test repeated?
Your provider may repeat this test if initial results are unclear or if you’re undergoing fertility treatment. Follow-up testing is often scheduled based on your symptoms and medical history.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy