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Serum/plasma progesterone concentration (qualitative/quantitative screening or confirmatory)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced mainly by the ovaries, in your blood. It helps assess reproductive health, fertility, and hormone balance.

Quick summary

["Progesterone levels can indicate pregnancy, menstrual cycle phases, or potential hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63887-4
Short code
Progesterone Ds CTS
Synonyms
Progesterone Ds CTS
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.1
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
california-teachers-study
CPT
84144
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to diagnose or monitor conditions like pregnancy, evaluate menstrual irregularities, check for ovarian cysts, assess fertility, or diagnose hormonal disorders such as polycystic ovary syndrome (PCOS). It can also be used during early pregnancy to confirm ovulation or rule out miscarriage risk.

What Does a Low or High Level Mean?

Low progesterone levels may suggest issues like premature ovarian failure, hormonal imbalances, or problems with ovulation. High levels could indicate pregnancy, certain tumors, or other hormonal conditions that require further evaluation by a healthcare provider.

How Is the Test Performed?

A blood sample is taken from a vein, usually in your arm. The sample is then sent to a lab for analysis using an immunoassay method to measure progesterone concentration.

What Are Common Reference Ranges?

Reference ranges vary by lab and cycle phase. Typically, they may differ for pre-ovulation, mid-cycle, and post-ovulation stages, or during pregnancy. Your doctor will provide your specific target range based on your situation.

Reference range

Follicular: 0.1-1.5 ng/mL; Luteal: 2-20 ng/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Progesterone plays a critical role in preparing the uterus for pregnancy and maintaining early pregnancy. Low levels can interfere with implantation or pregnancy maintenance, while abnormal spikes may indicate underlying conditions requiring medical attention.

Short name

Progesterone Level (Serum/Plasma)

Frequently asked questions

What does a progesterone test measure?
A progesterone test measures the hormone progesterone in your blood, which helps track reproductive health, fertility, and hormonal balance.
Can I eat or drink before the test?
You may eat and drink normally unless instructed otherwise by your healthcare provider. Avoid alcohol before the test, as it can affect hormone levels.
How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab and healthcare provider’s workflow. Follow-up may be needed if results are outside expected ranges.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy