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Progesterone level (serum/plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced mainly by the ovaries, in your blood. Progesterone plays a key role in regulating the menstrual cycle, pregnancy, and other reproductive functions.

Quick summary

["Progesterone helps prepare the uterus for pregnancy and supports early pregnancy until the placenta takes over hormone production."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
64662-0
Short code
Progesterone pattern use PhenX
Synonyms
Progesterone pattern use PhenX
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.1
Ref high
20
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
phenx
CPT
84144
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

When Is This Test Ordered?

Doctors may order this test to evaluate reproductive health, diagnose fertility issues, check for hormonal imbalances, or monitor conditions like endometriosis, polycystic ovary syndrome (PCOS), or pregnancy complications. It can also be used during ovulation tracking or before certain fertility treatments.

What Does a Low or High Progesterone Level Indicate?

Low levels may suggest issues like ovarian dysfunction, early menopause, or problems with ovulation. High levels could indicate conditions like ovarian tumors, pregnancy complications (such as molar pregnancy), or certain hormonal therapies.

How Is This Test Performed?

A blood sample is drawn from a vein, usually in your arm. The blood is then sent to a lab where it is analyzed to measure progesterone concentration using an immunoassay method.

What Are Common Reasons for Testing?

Common reasons include assessing fertility, diagnosing menstrual irregularities, evaluating symptoms of hormonal disorders, or monitoring pregnancy-related conditions. It may also be part of a broader evaluation for unexplained infertility or recurrent miscarriages.

Reference range

Follicular: 0.1-1.5 ng/mL; Luteal: 2-20 ng/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum/plasma progesterone

Frequently asked questions

Why might my doctor recommend this test?
Your doctor may recommend this test if you have symptoms like irregular periods, trouble getting pregnant, or if you’re undergoing fertility treatments. It can also help diagnose conditions like PCOS or evaluate hormonal changes during pregnancy.
What do my results mean?
Results are typically compared to your individual baseline or reference ranges provided by your healthcare provider. Low levels may indicate ovulation problems, while very high levels could signal pregnancy complications or other hormonal issues. Always discuss your results with your doctor.
How often should I get this test?
The frequency depends on your medical needs. Some patients may need testing monthly during ovulation tracking, while others may only need it once or twice a year for monitoring. Follow your doctor’s recommendations.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy