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Progesterone, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone hormone in your blood. Progesterone is a key hormone involved in menstrual cycles, pregnancy, and reproductive health.

Quick summary

["Progesterone levels help track ovulation, fertility, and potential pregnancy issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99391-5
Short code
Progest Ovarian asp-mCnc
Synonyms
Progest Ovarian asp-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test to evaluate reproductive health, diagnose hormonal imbalances, assess fertility, or monitor conditions like polycystic ovary syndrome (PCOS), endometriosis, or pregnancy complications. It can also help track menstrual cycle phases or evaluate ovarian function.

When Might You Need This Test?

You might need this test if you’re experiencing irregular periods, trouble getting pregnant, symptoms of hormonal disorders, or if your provider suspects an issue with your ovaries or reproductive system.

What to Expect Before the Test

No special preparation is usually needed, but your provider may advise timing it around your menstrual cycle (e.g., mid-cycle for ovulation tracking). Avoid smoking or certain medications that could affect results for 24 hours before testing.

What Happens During the Test?

A blood sample will be drawn from a vein in your arm by a healthcare professional. The blood is then sent to a lab for analysis using an immunoassay method to measure progesterone levels.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Progesterone

Frequently asked questions

What does a 'normal' result mean?
There’s no single 'normal' range for progesterone because it varies depending on your cycle phase, age, and health status. Your results will be interpreted by your provider in the context of your overall health and medical history.
How often should I get this test?
Your provider will determine how often you need this test based on your specific needs—whether for fertility tracking, monitoring a condition, or routine health checks.
Can diet or lifestyle affect progesterone levels?
Yes, factors like stress, certain medications (e.g., birth control), smoking, and diet can influence hormone levels. Avoiding these influences before testing can help ensure more accurate results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy