Skip to content

Progesterone, Serum or Plasma Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced mainly by the ovaries, in your blood. Progesterone helps regulate your menstrual cycle and is crucial during pregnancy.

Quick summary

["Progesterone levels help track ovulation, monitor fertility treatments, or diagnose hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
99390-7
Short code
Progest Ovarian asp-sCnc
Synonyms
Progest Ovarian asp-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re experiencing irregular menstrual periods, trying to conceive, or managing conditions like endometriosis, polycystic ovary syndrome (PCOS), or pregnancy complications. It can also be used during fertility treatments to check hormone levels.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if serum is required. If you’re taking oral medications that affect hormones, let your provider know. Avoid smoking or excessive caffeine before the draw.

What Happens During the Test

A healthcare professional will draw blood from a vein in your arm. The sample is then sent to a lab for analysis. The test typically takes less than 24 hours to complete, depending on lab processing times.

What the Results Mean

Results are compared to a reference range specific to your age, menstrual cycle phase (if applicable), and health status. Low levels may indicate ovulation issues, while high levels could signal pregnancy, ovarian tumors, or other conditions. Your provider will interpret results in the context of your overall health.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Progesterone Level

Frequently asked questions

What causes abnormal progesterone levels?
Abnormal progesterone levels can result from hormonal imbalances, pregnancy complications, ovarian cysts, or certain medications. Conditions like PCOS or thyroid disorders may also influence results. Always discuss symptoms and test results with your provider.
How often should I get this test?
Frequency depends on your medical needs. If you’re tracking ovulation or fertility, your provider may recommend testing during mid-cycle. For ongoing conditions like PCOS, tests might be repeated every few months.
Can diet or lifestyle affect progesterone levels?
Yes, diet, stress, and exercise can influence hormone levels. Avoiding excessive caffeine, alcohol, and smoking may help stabilize results. Maintaining a balanced diet rich in nutrients like folate and zinc may also support hormonal health.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy