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Progesterone, Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced by the ovaries, in your blood. Progesterone plays a key role in regulating the menstrual cycle, pregnancy, and the menstrual cycle phases.

Quick summary

["Progesterone levels help diagnose fertility issues, monitor ovulation, and assess hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2838-1
Short code
Progest Sal-mCnc
Synonyms
Progest Sal-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you’re experiencing irregular periods, trouble getting pregnant, or symptoms like breast tenderness, acne, or mood changes that could be linked to hormonal fluctuations. It may also be used during pregnancy to track fetal development or evaluate ovarian function.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if your lab requires it. Wear a comfortable shirt for easy access to your arm. If you’re taking hormonal medications (like birth control), let your provider know, as this may affect results.

What the Test Involves

A healthcare professional will insert a small needle into your arm to draw blood. The process takes about 5 minutes, and you may feel a brief pinch. The blood sample is then sent to a lab for analysis. Results are typically ready within 1–3 business days.

What the Results Mean

Progesterone levels vary depending on your menstrual cycle phase or reproductive status. For example, levels rise during ovulation and peak in early pregnancy. Your provider will interpret results in the context of your medical history and symptoms, not just the absolute number.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Low progesterone levels may indicate issues like polycystic ovary syndrome (PCOS), premature ovarian failure, or problems with ovulation. High levels could signal conditions like ovarian tumors or certain endocrine disorders. During pregnancy, elevated progesterone supports uterine lining growth and prevents premature contractions. Always discuss results with your healthcare provider.

Short name

Progesterone Level

Frequently asked questions

How long does it take to get results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your provider will contact you once they’re ready, but some labs may email or mail results directly to you.
Can I take anything before the test?
No special diet is required, but avoid alcohol for 24 hours before testing. If you’re on hormonal medications, check with your provider to confirm if you should stop or adjust them temporarily.
Does this test affect fertility treatments?
Yes, progesterone levels are closely monitored during fertility treatments (like IVF or hormone therapy) to ensure proper hormone balance. Your provider may adjust treatments based on your results to improve success rates.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy