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Progesterone, Serum Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced by the ovaries, in your blood serum. It helps assess reproductive health, especially during the menstrual cycle, pregnancy, or hormone-related conditions.

Quick summary

["Progesterone levels can indicate fertility, pregnancy, or hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14890-8
Short code
Progest SerPl-sCnc
Synonyms
Progest SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

When Is This Test Done?

A serum progesterone test may be ordered to evaluate menstrual cycle irregularities, diagnose infertility, check for pregnancy (early or ectopic), or monitor hormone therapy. It’s often taken during specific phases of the menstrual cycle or pregnancy to track hormone fluctuations.

What to Expect Before the Test

No special preparation is usually needed, but your doctor may advise timing the test around your menstrual cycle (e.g., mid-luteal phase) or pregnancy stage. Avoid smoking or alcohol 24 hours before testing if instructed.

What Happens During the Test

A blood sample is drawn from a vein, typically in your arm. You may feel a slight pinch, but it’s quick and painless. The sample is sent to a lab for analysis.

What the Results Mean

Results provide a quantitative measure of progesterone concentration in your blood. While reference ranges vary by lab, they help identify whether your hormone levels are within expected ranges for your cycle stage or condition.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Progesterone plays a critical role in reproductive health, including ovulation support, preparing the uterine lining for pregnancy, and maintaining early pregnancy. Abnormal levels may signal conditions like polycystic ovary syndrome (PCOS), ovarian dysfunction, or miscarriage risk.

Short name

Serum Progesterone

Frequently asked questions

Why did my doctor recommend this test?
Your doctor may have suggested this test to investigate symptoms like irregular periods, infertility, or to monitor a known hormonal condition. It helps track how your body’s hormone levels change over time.
What do my results indicate?
Your results will be compared to lab-specific reference ranges. Low levels may suggest ovulation issues or early pregnancy, while high levels could indicate pregnancy, hormonal therapy, or other conditions. Always discuss results with your healthcare provider.
Can I adjust my diet or lifestyle before the test?
Generally, no dietary changes are needed, but avoid smoking or excessive alcohol 24 hours before testing if advised. Follow your doctor’s specific instructions for optimal accuracy.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy