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Progesterone, Serum (10 p.m. postmenopausal or cyclic phase)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone hormone in your blood, which plays a key role in regulating menstrual cycles, pregnancy, and fertility in women.

Quick summary

["Progesterone helps prepare the uterus for pregnancy and supports early development; levels can indicate reproductive health or potential fertility issues."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33851-7
Short code
Progest sp10 p chal SerPl-mCnc
Synonyms
Progest sp10 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test to evaluate reproductive health, diagnose hormonal imbalances, assess fertility, or monitor conditions like endometriosis, ovarian cysts, or menopause-related symptoms. It may also be used during pregnancy to check for complications or to guide treatment for conditions like polycystic ovary syndrome (PCOS).

What to Expect Before the Test

For women undergoing a menstrual cycle, testing is often done in the **luteal phase** (around day 21–23 of the cycle) or post-menopause to avoid fluctuations from ovulation. If you’re taking hormonal medications, inform your provider, as they may affect results. No special preparation is needed, but fasting is not required.

What the Results Mean

Progesterone levels vary by life stage and cycle phase. Low levels may suggest issues like early menopause, ovarian dysfunction, or hormonal therapy resistance. High levels could indicate pregnancy, ovarian tumors, or certain medications. Always discuss results with your provider for personalized interpretation.

Common Conditions Monitored

This test helps diagnose or manage conditions like **infertility**, **endometriosis**, **ovarian cysts**, or **hormonal imbalances**. It may also be used in fertility treatments to track luteal phase support or rule out conditions like **premenstrual dysphoric disorder** (PMDD).

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Progesterone Level

Frequently asked questions

How long does it take to get my results back?
Results are typically available within 1–3 business days, depending on your lab. Your provider will contact you to discuss findings once they’re ready.
Can I take anything before the blood draw?
No special preparations are needed, but avoid alcohol for 24 hours before testing, as it may affect hormone levels. If you’re on hormonal medications, confirm with your provider.
Will this test be affected by my menstrual cycle?
Yes, timing matters. For women with cycles, testing is often done in the **luteal phase** (days 21–23) or post-menopause to avoid variability from ovulation. Your provider will guide the best timing for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy