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Progesterone, Serum (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced by the ovaries, in your blood. Progesterone plays a key role in regulating the menstrual cycle and pregnancy.

Quick summary

["Progesterone levels help assess fertility, ovulation, and potential pregnancy health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25509-1
Short code
Progest sp3 p chal SerPl-sCnc
Synonyms
Progest sp3 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may recommend this test to evaluate reproductive health, diagnose conditions like polycystic ovary syndrome (PCOS), check for ovulation, or monitor pregnancy-related hormone changes. It can also help assess hormonal imbalances or evaluate symptoms such as irregular periods or infertility.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood. If you’re taking certain medications that affect hormone levels, let your provider know before the test.

What the Results Mean

Progesterone levels vary depending on the phase of your menstrual cycle or pregnancy. Higher levels may indicate ovulation or pregnancy, while lower levels could suggest issues like hormonal imbalances or ovulatory disorders. Your results will be compared to your individual baseline or clinical context by your healthcare provider.

Common Conditions Monitored

This test is often used to diagnose or monitor conditions like endometriosis, ovarian cysts, or hormonal disorders. It may also be checked during fertility treatments or to evaluate symptoms such as missed periods, irregular cycles, or recurrent miscarriages.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Progesterone

Frequently asked questions

How long will it take to get my results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing time. Your healthcare provider will discuss the findings with you during your follow-up visit.
Can I eat or drink before this test?
You can eat and drink normally before this test, as it’s a standard blood draw with no dietary restrictions.
What if my progesterone levels are too high or too low?
Extremely high or low progesterone levels may signal underlying health concerns, such as hormonal imbalances, ovarian cysts, or pregnancy complications. Your provider will interpret the results in relation to your symptoms and medical history to determine the next steps.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy