Skip to content

Progesterone, Serum (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced primarily by the ovaries, in your blood serum. Progesterone plays a key role in regulating the menstrual cycle and pregnancy.

Quick summary

["Progesterone levels help track reproductive health and fertility status."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
33854-1
Short code
Progest sp4 p chal SerPl-sCnc
Synonyms
Progest sp4 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Doctors may order this test to evaluate hormonal imbalances, diagnose fertility issues, check for conditions like polycystic ovary syndrome (PCOS), monitor pregnancy-related complications, or assess ovarian function in women. It can also be used during fertility treatments or to diagnose hormonal disorders in men.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to avoid certain medications or activities for a few days before testing. For example, if you’re taking hormonal birth control, your doctor might recommend stopping it temporarily. If you’re pregnant or breastfeeding, let your healthcare provider know.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but it’s usually over quickly. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are typically reported in nanograms per deciliter (ng/dL) or other standardized units. Your actual range may vary based on your age, health, and the reason for testing. Your doctor will interpret the results in the context of your overall health and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Progesterone

Frequently asked questions

What Does This Test Tell Us About My Health?
High progesterone levels might indicate conditions like ovarian tumors, pregnancy, or certain hormonal imbalances. Low levels could suggest issues like premature ovarian insufficiency, PCOS, or problems with ovulation. Always discuss your results with your healthcare provider, as they’ll help determine if further testing or treatment is needed.
FAQ: What If My Results Are Abnormal?
If your results are outside the expected range, your doctor may recommend additional tests or treatments. For example, if progesterone levels are low, they might explore causes like thyroid issues, stress, or nutritional deficiencies. Follow-up care depends on your specific situation.
FAQ: How Often Should I Get This Test?
The frequency depends on your medical needs. Some women get progesterone tests during the menstrual cycle to track ovulation or during fertility treatments. Others may need it once or twice a year if they have ongoing reproductive health concerns. Always ask your doctor how often this test is appropriate for you.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy