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Progesterone, Serum (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced by the ovaries, in your blood. Progesterone plays a key role in regulating the menstrual cycle, pregnancy, and other reproductive functions.

Quick summary

["Progesterone levels help assess fertility, monitor ovulation, or evaluate hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12819-9
Short code
Progest sp6 p chal SerPl-mCnc
Synonyms
Progest sp6 p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Might This Test Be Ordered?

Your healthcare provider may order this test to check for ovulation, diagnose hormonal disorders, evaluate fertility issues, or monitor conditions like polycystic ovary syndrome (PCOS) or pregnancy-related hormonal changes. It can also be used during fertility treatments or to assess complications in pregnancy.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if your test involves a specific timing (e.g., mid-luteal phase). Wear comfortable clothing and plan to rest after the draw.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. The process is quick and typically painless. You may feel a slight pinch, but the area will numb quickly. The blood sample is then sent to a lab for analysis.

What Are Possible Results?

Results are expressed in mass concentration units (e.g., ng/mL or pmol/L) and will be compared to your healthcare provider’s reference ranges. These can vary by lab and individual health status.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Progesterone levels can indicate ovulation (peaking mid-cycle), pregnancy (rising during early pregnancy), or hormonal imbalances (e.g., low levels may suggest ovulation disorders or adrenal issues). Abnormal results may prompt further evaluation, including additional tests or imaging.

Short name

Serum Progesterone

Frequently asked questions

How long does it take to get results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will contact you once they are ready.
What does a low progesterone level mean?
Low progesterone could signal issues like irregular ovulation, hormonal disorders, or early pregnancy loss. Your provider may recommend further testing or adjustments to your treatment plan.
Can diet or supplements affect progesterone levels?
Certain foods, supplements (e.g., soy, licorice), or medications (e.g., birth control) may influence hormone levels. Always discuss your diet, supplements, or medications with your provider before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy