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Serum Progesterone Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced mainly by the ovaries, in your blood. Progesterone helps regulate your menstrual cycle and is important during pregnancy.

Quick summary

["Progesterone levels can indicate fertility, pregnancy, or hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47990-7
Short code
Progest sp8 p chal SerPl-sCnc
Synonyms
Progest sp8 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test to evaluate ovarian function, diagnose fertility issues, assess pregnancy, or check for hormonal disorders like polycystic ovary syndrome (PCOS). It can also help monitor conditions like endometriosis or evaluate symptoms of hormonal imbalances.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if it involves a blood draw. Inform your provider about any medications, supplements, or recent illnesses that could affect results.

How the Test Is Performed

A blood sample is taken from a vein in your arm by a healthcare professional. The sample is then sent to a lab for analysis using a sensitive immunoassay method to measure progesterone concentration.

What the Results Mean

Results are typically reported in nanograms per milliliter (ng/mL) or picograms per milliliter (pg/mL). Interpretation depends on your cycle phase, age, and medical history. High or low levels may signal underlying health concerns that need further evaluation.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Progesterone Level

Frequently asked questions

How often will I need this test?
The frequency depends on your medical condition or symptoms. Some patients need testing monthly, seasonally, or only during specific phases of their cycle (e.g., mid-cycle for ovulation tracking). Your provider will outline the schedule based on your needs.
Can lifestyle changes affect progesterone levels?
Yes, factors like stress, poor sleep, certain medications (e.g., birth control, antidepressants), and chronic illnesses (e.g., thyroid disorders) can influence hormone levels. Maintaining a balanced diet, managing stress, and staying physically active may support hormonal balance.
What if my test results are outside the expected range?
If your results are abnormal, your provider will review them with you and may recommend additional tests or treatments. This could include further bloodwork, imaging, or lifestyle adjustments to address the underlying cause.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy