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Progesterone, Serum (Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of progesterone, a hormone produced primarily by the ovaries, in your blood. Progesterone plays a key role in the menstrual cycle, pregnancy, and overall reproductive health.

Quick summary

["Understanding your progesterone levels helps track ovulation, fertility, and potential hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47991-5
Short code
Progest sp9 p chal SerPl-sCnc
Synonyms
Progest sp9 p chal SerPl-sCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Doctors may recommend this test to evaluate ovulation, diagnose conditions like polycystic ovary syndrome (PCOS), assess fertility, or check for hormonal disorders. It can also be used during pregnancy to monitor early development or rule out miscarriage risks.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Wear comfortable clothing and plan to stay for about 15 minutes while the blood is drawn.

What Happens During the Test

A healthcare provider will insert a small needle into a vein in your arm to collect blood. You may feel a brief pinch, but it’s usually over quickly. The blood sample is then sent to the lab for analysis.

What the Results Mean

Results are interpreted based on your medical history, symptoms, and the reason the test was ordered. Low or high levels may indicate conditions like delayed ovulation, hormonal imbalances, or pregnancy complications. Your doctor will discuss findings with you in detail.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Serum Progesterone Level

Frequently asked questions

How long does it take to get my results?
Results typically arrive within 1–3 business days, depending on your lab’s processing time. Your doctor will contact you once they’re ready to discuss them.
Can I eat or drink before this test?
Most labs recommend fasting for 8–12 hours before drawing blood, but always follow your doctor’s specific instructions. If fasting isn’t required, you can eat and drink normally.
Is there anything I should avoid before the test?
Avoid strenuous activity, smoking, or caffeine 24 hours before the test if your lab instructions specify it. Wear loose clothing to the appointment and stay hydrated unless advised otherwise.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy