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Prolactin, 15-Hour Post-RH (Recombinant Human) Serum Measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures your prolactin hormone level in serum after a 15-hour period following administration of recombinant human growth hormone (RH). It helps evaluate conditions affecting hormone regulation.

Quick summary

["This test assesses prolactin levels after a controlled hormone stimulation to detect potential hormonal imbalances."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47729-9
Short code
Prolactin 1.5h p TRH IV SerPl-mCnc
Synonyms
Prolactin 1.5h p TRH IV SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you have symptoms like unexplained galactorrhea (milk production in non-breastfeeding individuals), infertility, or signs of hormonal disorders. It can also be used to monitor prolactin-related conditions or rule out pituitary issues.

What Does the Test Involve?

You’ll receive a recombinant human growth hormone injection. Blood is drawn 15 hours later to measure prolactin levels in your serum. This timing helps assess how your body responds to the hormone.

What to Expect Before the Test

No special preparation is typically needed, but follow your provider’s instructions regarding diet, medications, or activity restrictions. Avoid smoking or caffeine before the test as it may affect hormone levels.

What to Expect During the Test

A healthcare professional will insert a needle into a vein in your arm or hand to draw blood. You may feel a brief pinch, but it usually doesn’t cause significant discomfort. The blood sample will be sent to a lab for analysis.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated prolactin levels after RH stimulation can indicate pituitary tumors, hyperprolactinemia, or other conditions affecting hormone secretion. Low levels may suggest pituitary dysfunction or other rare hormonal disorders. This test helps diagnose and monitor conditions related to prolactin regulation.

Short name

Prolactin (15h post-RH)

Frequently asked questions

How long will it take to get my results?
Results are usually available within 1–3 business days, depending on your lab’s processing time. Your healthcare provider will contact you with the final report once completed.
What do my results mean?
Your results will be compared to reference ranges provided by your lab. Elevated prolactin levels may require further evaluation, such as imaging tests or additional hormone checks. Always discuss your results with your provider for personalized interpretation.
Can I take anything before or after the test?
Avoid smoking, caffeine, or certain medications that may influence hormone levels. Follow your provider’s instructions regarding timing of meals or other activities. Do not take the RH injection if you’re pregnant or have known allergies to the hormone.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy