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Serum Prolactin Level (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of prolactin, a hormone produced by your pituitary gland, in your blood. Prolactin helps regulate breast milk production and influences other bodily functions.

Quick summary

["Prolactin levels can help diagnose hormonal imbalances or conditions affecting your pituitary gland."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
44929-8
Short code
Prolactin 15M p TRH IV SerPl-aCnc
Synonyms
Prolactin 15M p TRH IV SerPl-aCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a prolactin test to check for conditions like hyperprolactinemia (high prolactin levels), which can cause issues with fertility, menstrual problems, or other hormonal symptoms. It may also be used to evaluate symptoms such as headaches, vision changes, or unexplained galactorrhea (milk production outside of pregnancy). Sometimes, it’s part of a broader evaluation for pituitary disorders or tumors.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if your doctor specifies it. Wear comfortable clothing for blood drawing. If you’re taking medications that affect prolactin (like certain antidepressants or antipsychotics), let your doctor know beforehand.

What Happens During the Test?

A healthcare provider will draw blood from a vein in your arm using a small needle. You may feel a brief pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are compared to standard reference ranges, but they can vary by lab. High prolactin levels may suggest pituitary tumors, thyroid issues, or certain medications. Low levels might indicate conditions like hyperthyroidism or pregnancy. Your doctor will discuss the results in the context of your symptoms and medical history.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Prolactin

Frequently asked questions

What Causes Abnormal Results?
High prolactin levels can be caused by pituitary tumors, kidney problems, certain medications (e.g., antidepressants, birth control), or conditions like hyperthyroidism. Low levels may result from pregnancy, hyperthyroidism, or pituitary damage. Always discuss symptoms with your doctor, as results alone don’t always indicate a diagnosis.
How Often Should I Get This Test?
Your doctor will determine how often you need this test based on your symptoms, medical history, and treatment plan. Follow-up tests may be scheduled if your levels are abnormal or if you’re managing a condition like hyperprolactinemia.
Can I Take Anything Before the Test?
No special preparations are required unless instructed by your doctor. If you’re unsure, ask your healthcare provider about any medications or supplements to avoid before testing.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy