Prolactin Level (24-Hour Profile with HIV Serology)
This test measures your prolactin hormone level over 24 hours and checks for HIV antibodies in your blood. Prolactin helps regulate breast milk production and affects mood, sleep, and fertility. Elevated levels may signal conditions like pituitary tumors or thyroid issues, while HIV antibodies help detect infection.
["A 24-hour prolactin test and HIV screening may be needed if you have unexplained symptoms or risk factors for prolactin disorders or HIV."]
Key facts at a glance
- LOINC
- 47870-1
- Short code
- Prolactin 2.5h p TRH IV SerPl-mCnc
- Synonyms
- Prolactin 2.5h p TRH IV SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0.8
- Ref high
- 1.2
- Critical range
- — – 5 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 85610
- SNOMED
- 396252006
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your doctor may order this test if you have symptoms like unexplained breast milk production in men, infertility, mood swings, or headaches. It could also be recommended if you have a history of pituitary tumors, thyroid disorders, or HIV exposure. A 24-hour profile helps track how prolactin changes throughout the day, while HIV screening ensures early detection of infection.
What to Expect Before the Test
No special preparation is needed for the prolactin test, but you may be asked to avoid certain medications that could affect results. For the 24-hour profile, collect blood samples at regular intervals over 24 hours. For HIV testing, a simple blood draw is typically done. Always follow your healthcare provider’s instructions carefully.
What the Results Mean
Prolactin results alone don’t provide a diagnosis—your doctor will interpret them alongside your symptoms and medical history. Elevated prolactin may suggest conditions like a pituitary tumor or thyroid problems. HIV antibody results are qualitative (positive/negative) and help determine infection status. Discuss any abnormal results with your doctor.
Common Conditions Linked to Prolactin
High prolactin levels can be linked to pituitary adenomas, thyroid disorders (like hypothyroidism), kidney disease, or certain medications. Low prolactin may occur with pregnancy, breastfeeding, or certain medical conditions. HIV infection itself doesn’t directly affect prolactin levels but requires separate monitoring.
Reference range
INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A
Inform your healthcare provider if you are taking blood thinners. No special preparation required.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Prolactin Profile (HIV Screen)
Frequently asked questions
How often will I need this test?
What if my prolactin level is high?
Can I drink alcohol before the test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy