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Prolactin, Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of prolactin, a hormone produced by the pituitary gland, in your blood. It helps evaluate conditions related to hormone imbalances or potential pituitary disorders.

Quick summary

["Prolactin levels can indicate issues with hormone production or function in your body."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
41608-1
Short code
Prolactin 30M p chal SerPl-mCnc
Synonyms
Prolactin 30M p chal SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2
Ref high
18
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84146
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order a prolactin test to check for problems like hyperprolactinemia (too much prolactin), which can affect fertility, menstrual cycles, or cause symptoms like breast tenderness or missed periods. It may also be used to diagnose pituitary tumors, thyroid disorders, or other hormonal imbalances.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves a blood draw, but this depends on your provider’s instructions. Wear comfortable clothing and plan to stay near the testing site for a short time.

What Happens During the Test?

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it’s a quick and painless procedure. The blood sample will be sent to a lab for analysis.

What Are Possible Results?

Results are compared to standard reference ranges, but your specific values will be reviewed by your provider. High or low prolactin levels may signal underlying health concerns that need further evaluation.

Reference range

Adult males: 2-18 ng/mL; Females: 2-29 ng/mLN/A

Specimen: serum

For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated prolactin levels can cause infertility, irregular menstrual cycles, or galactorrhea (milk production outside of pregnancy). Low levels may suggest pituitary dysfunction or other hormonal disorders. Your provider will interpret results in the context of your symptoms and medical history.

Short name

Prolactin Level

Frequently asked questions

How often should I get this test?
The frequency depends on your symptoms and medical needs. Your healthcare provider will determine how often to repeat the test based on your diagnosis or monitoring plan.
What are common symptoms linked to abnormal prolactin levels?
Symptoms of high prolactin can include missed periods, breast tenderness, reduced fertility, or milk production outside of pregnancy. Low prolactin may cause irregular or absent menstrual cycles, low libido, or fatigue, though symptoms vary widely.
Can lifestyle changes affect prolactin levels?
Yes, certain activities like stress, caffeine, or certain medications (e.g., antidepressants) may influence prolactin levels. Avoiding these factors before testing can help ensure more accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy