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Serum Prolactin Level (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of prolactin, a hormone produced by your pituitary gland, in your blood. Prolactin helps regulate breast milk production and affects other bodily functions.

Quick summary

["Prolactin levels can signal potential hormonal imbalances or health conditions that need medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1614-7
Short code
Prolactin 30M p TRH IV SerPl-mCnc
Synonyms
Prolactin 30M p TRH IV SerPl-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order a prolactin test to check for conditions like hyperprolactinemia (high prolactin levels), which can cause issues such as infertility, irregular menstrual cycles, or symptoms like breast tenderness. It may also be used to monitor treatment for conditions like pituitary tumors or to investigate unexplained symptoms like headaches or vision changes.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw blood, which usually causes only a brief pinch. If you’re taking certain medications that affect prolactin levels, your doctor may ask you to stop them temporarily before testing.

What Happens During the Test?

Blood is collected from a vein in your arm using a needle. The sample is then sent to a lab for analysis. The test typically takes a few minutes, and you can resume normal activities afterward.

What the Results Mean

Results are compared to standard reference ranges, though individual ranges can vary. High prolactin levels may indicate pituitary issues, certain medications, or other health problems. Low levels might suggest conditions like hypothyroidism or pregnancy. Always discuss results with your healthcare provider.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: serum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Prolactin

Frequently asked questions

What causes prolactin levels to be tested?
Prolactin levels are tested to diagnose or monitor conditions such as pituitary tumors, hyperprolactinemia, infertility, menstrual irregularities, breast tenderness, or symptoms like headaches or vision problems. It may also be used to assess the effectiveness of treatments for hormonal imbalances.
How do prolactin levels affect pregnancy?
High prolactin levels can interfere with ovulation and may lead to infertility. In pregnant women, prolactin levels naturally rise, which can sometimes cause issues like breast tenderness or milk production. Always consult your doctor if you have concerns about prolactin levels during pregnancy.
Can medications affect prolactin levels?
Yes, several medications—such as certain antidepressants, antipsychotics, antihypertensives, and hormonal treatments—can increase prolactin levels. If you’re on medication, inform your doctor before the test to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy