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Promethazine in Urine (24-Hour Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of promethazine, a medication used to treat allergies, in your urine over a 24-hour period.

Quick summary

["Helps track drug exposure and effectiveness over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
75813-6
Short code
Promethazine Bld/Urn Ql Scn
Synonyms
Promethazine Bld/Urn Ql Scn
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
screen
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may request this test if you’ve been prescribed promethazine for allergies or other conditions and want to monitor how much of the drug is being eliminated from your body. It could also be used to check for drug levels in cases of suspected overdose or improper use.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after your first morning urine. Follow your provider’s instructions carefully to ensure accurate results. Bring the collected sample to your lab appointment.

How the Test Works

The collected urine is analyzed to measure the concentration of promethazine. The test detects the drug’s presence and quantifies how much was excreted in your urine over the specified time.

What the Results Mean

Results help determine if the prescribed dose is appropriate, if the drug is being processed correctly by your body, or if there may be issues like improper metabolism or excessive exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Promethazine Urine

Frequently asked questions

How long does a 24-hour urine collection take?
You’ll need to collect urine for a full 24-hour period, which means starting the collection after your first morning urine and continuing until you’ve collected all urine for the next 24 hours. You may need to use a timed container or split the sample if your provider instructs you to.
Can I drink alcohol or take other medications during the urine collection?
Follow your healthcare provider’s instructions carefully. Some medications or substances may interfere with the test results, so avoid them unless approved. Alcohol is generally not restricted unless specified.
What if I miss any urine during the collection?
If you miss urine, you’ll need to restart the collection from the next morning’s urine. Missing even a small amount can affect accuracy, so plan ahead to ensure full collection.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy