Cerebrospinal Fluid (CSF) Differential Count with Manual Evaluation

What This Test Measures

The manual evaluation looks at the percentage of different white blood cell types (such as neutrophils, lymphocytes, or monocytes) in your CSF. Each cell type can indicate specific health concerns, like bacterial infections (neutrophils), viral infections (lymphocytes), or other immune responses.

Why It Matters in Your Care

Your healthcare provider may use this test to confirm or guide treatment for conditions like meningitis, encephalitis, or other neurological disorders. The manual method provides detailed cell differentiation that automated tests might not capture.

How the Test Works

A small sample of your CSF is taken via a spinal tap or lumbar puncture. The sample is then examined under a microscope by a trained technician, who counts and categorizes the white blood cells manually. This process helps identify patterns or abnormalities in cell types.

Preparation for the Test

No special preparation is needed for this test. You may experience mild discomfort during the spinal tap, but the procedure is generally quick and well-tolerated. Follow any specific instructions your provider gives you before the test.