Propionylcarnitine (Carnitine Propionyl Ester) in Serum/Plasma
This test measures the amount of propionylcarnitine, a breakdown product of certain amino acids, in your blood. It helps assess how well your body is processing fats and amino acids.
["This test may help diagnose metabolic disorders or monitor conditions affecting fat metabolism."]
Key facts at a glance
- LOINC
- 53162-4
- Short code
- Propionylcarn/C0 DBS-sRto
- Synonyms
- Propionylcarn/C0 DBS-sRto
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms of metabolic disorders, such as unexplained fatigue, muscle weakness, or developmental delays in children. It could also be used to evaluate conditions like medium-chain acyl-CoA dehydrogenase (MCAD) deficiency or other inherited metabolic diseases.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the test if instructed. Bring any medications you’re taking, as some may affect results.
How the Test Is Performed
A blood sample is drawn from a vein in your arm by a healthcare professional. The sample is then sent to a lab for analysis using a specialized method to detect propionylcarnitine levels.
Possible Results and Interpretation
Results are compared to a reference range, but exact values can vary by lab. Elevated levels may suggest metabolic imbalances, while very low levels could indicate impaired fat metabolism or certain genetic conditions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
High propionylcarnitine levels in blood may indicate an inability to properly metabolize certain amino acids or fats, which can lead to complications like ketoacidosis, neurological issues, or growth problems in children. This test is particularly useful in diagnosing inherited metabolic disorders that require early intervention.
Short name
Propionylcarnitine
Frequently asked questions
What does a high propionylcarnitine level mean?
Can diet affect this test?
Is this test painful?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy