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Serum Propionylglycine Concentration (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of propionylglycine in your blood, a compound produced during the breakdown of certain amino acids. It is often used in metabolic testing, particularly for conditions affecting fat and amino acid metabolism.

Quick summary

["This test helps diagnose and monitor metabolic disorders like propionic acidemia."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
54332-2
Short code
Propionylgly CSF-sCnc
Synonyms
Propionylgly CSF-sCnc
Category
glucose
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like vomiting, weakness, or unusual smells (such as sweaty feet) that could suggest a metabolic disorder. It may also be used as part of newborn screening or ongoing monitoring for known metabolic conditions.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood. If you’re a newborn, a heel prick may be used instead. Avoid eating or drinking for a few hours before the test if instructed by your provider.

What the Test Results Mean

Results are compared to a reference range for your age and health status. High levels may indicate a metabolic disorder, while very low levels could raise concerns about treatment effectiveness or underlying issues. Always discuss results with your doctor.

Common Conditions Monitored

This test is primarily used to diagnose or track propionic acidemia, a rare genetic disorder that affects how your body processes certain nutrients. It may also be part of broader metabolic evaluations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Propionic Acidemia and Beyond

Short name

Propionylglycine Level

Frequently asked questions

What Does My Test Result Indicate?
If your result is outside the expected range, your doctor may recommend further testing, adjustments to your treatment plan, or referrals to a metabolic specialist. High levels could mean your body isn’t processing certain nutrients properly, while low levels might signal the need for closer monitoring.
How Often Will I Need This Test?
The frequency depends on your diagnosis and treatment. Some patients need testing weekly or monthly to track how their condition responds to therapy. Your doctor will outline a schedule based on your specific needs.
Can Diet or Medications Affect This Test?
Certain medications (like some antibiotics or vitamins) or dietary changes (such as high-protein diets) may influence results. Always inform your healthcare provider about all medications, supplements, or recent dietary changes before testing.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy