Propoxyphene-to-Creatinine Ratio, Urine
A urine test that measures propoxyphene relative to creatinine, helping determine whether the opioid pain medicine is present in the body.
["This test can show whether propoxyphene is present in the urine, but timing, dose, and other factors affect the result."]
Key facts at a glance
- LOINC
- 58398-9
- Short code
- Propoxyph/Creat Ur
- Synonyms
- Propoxyph/Creat Ur
- Category
- kidney
- Sample
- urine
- Container
- Sterile urine container
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 10 mL
- Stability
- Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 0
- Lipemia max
- 0
- Icterus max
- 0
- TAT
- 4–24 hours
- Order
- routine
What is this test?
This urine test measures the amount of propoxyphene, a prescription opioid pain medicine, relative to the amount of creatinine in the same sample. Creatinine is used as a reference to help account for differences in urine concentration.
Why might I need this test?
A clinician may order this test to check for propoxyphene exposure, monitor medication use, or investigate use that was not expected. It may be relevant in certain medication-monitoring, workplace, legal, or substance-use evaluations.
How is the test performed?
A urine specimen is collected and analyzed in the laboratory to measure propoxyphene and creatinine. The laboratory then reports the amount of propoxyphene relative to the amount of creatinine.
How do I prepare for the test?
Follow the collection instructions provided by the clinician or laboratory, including any specified collection time. Do not stop or change your propoxyphene dose without medical advice, and tell the healthcare team about other medicines or supplements you use.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Detecting propoxyphene in urine can indicate recent exposure or use, but the finding alone cannot determine the exact dose taken, when it was taken, or whether someone is impaired. The result can also be affected by urine concentration, the timing of collection, and individual drug metabolism. A not-detected result does not necessarily rule out all exposure, so results should be interpreted alongside the clinical history and other tests.
Short name
Urine propoxyphene
Frequently asked questions
What is propoxyphene?
Why is creatinine included in this urine test?
Does a positive result mean someone took too much?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy