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Prostaglandin E2 (PGE₂) Mass Concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of prostaglandin E2, a type of hormone-like substance produced in your body that helps regulate inflammation, pain, and other bodily functions.

Quick summary

["Understanding your prostaglandin E2 levels may help assess inflammation or pain-related conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
70093-0
Short code
Prostaglandin E1 CSF-mCnc
Synonyms
Prostaglandin E1 CSF-mCnc
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like persistent pain, inflammation, or conditions such as arthritis, menstrual cramps, or certain gastrointestinal issues. It could also be used to monitor treatment responses in conditions where prostaglandins play a role.

What to Expect Before the Test

No special preparation is typically needed. You may provide a blood sample (serum or plasma) or, less commonly, urine. If you’re unsure about preparation, ask your provider.

What the Results Mean

Results are not typically provided as absolute numbers but are often interpreted relative to clinical context, symptoms, or other test results. Elevated levels may suggest inflammation or pain pathways being active, while lower levels might indicate reduced prostaglandin activity.

Common Conditions Monitored

This test is sometimes used in research or specialized settings to evaluate conditions where prostaglandins are suspected to be involved, such as autoimmune diseases, certain cancers, or inflammatory responses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

PGE₂ Level

Frequently asked questions

What does a prostaglandin E2 test measure?
It measures the concentration of prostaglandin E2, a specific type of hormone-like substance in your body that influences inflammation and pain.
How is this test different from other pain or inflammation tests?
Unlike general inflammation markers (e.g., CRP), this test focuses specifically on PGE₂, which can provide more targeted insights into prostaglandin-driven processes.
Can this test be done at home?
No, this test requires a blood or urine sample collected by a healthcare professional in a clinical setting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy