Protein C Activation Factor IX (Protein C:Factor IXa Complex)
This test measures the interaction between Protein C and activated Factor IX, a key part of blood’s natural clotting pathway. It helps assess how well your blood can prevent abnormal clotting.
["This test evaluates your blood’s ability to regulate clotting safely."]
Key facts at a glance
- LOINC
- 58481-3
- Short code
- Prot C Ag/Fact IX Ag PPP IA
- Synonyms
- Prot C Ag/Fact IX Ag PPP IA
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if you have a suspected bleeding disorder, such as hemophilia or other inherited clotting factor deficiencies. It could also be used to monitor treatment for conditions affecting blood clotting or to check for rare inherited bleeding risks.
What to Expect Before the Test
No special preparation is needed. You may have a blood draw from a vein in your arm. If you’re on anticoagulant medications, let your provider know before the test.
What the Test Results Mean
Results typically compare your protein complex levels to a standard reference range. Abnormally low levels may indicate bleeding risks, while very high levels could suggest rare clotting disorders or laboratory artifacts. Your provider will interpret results in the context of your symptoms and medical history.
Common Conditions This Test Helps Diagnose
This test supports diagnosing inherited bleeding disorders like hemophilia A or B, where Factor IX is deficient. It may also help identify or monitor conditions affecting Protein C’s role in clotting regulation.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance: Understanding Your Results
Short name
Protein C:IXa Complex
Frequently asked questions
What are the normal reference ranges for this test?
Why might my test results be different from what I expected?
Can this test be done at home or via a fingerstick?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy