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Protein in Plasma (Mass Concentration)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein found in your blood plasma, which helps assess overall protein status and kidney function.

Quick summary

["Your blood protein levels can signal health issues like kidney problems or dehydration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
4671-4
Short code
Prot C Plas-mCnc
Synonyms
Prot C Plas-mCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Protein is essential for maintaining fluid balance, supporting immune function, and transporting nutrients. Low levels may indicate kidney disease, malnutrition, or excessive fluid loss, while high levels could suggest conditions like dehydration or inflammation.

What to Expect During the Test

A small blood sample is drawn from your arm. No special preparation is needed, but fasting may be advised depending on your specific test order.

How Results Are Used

Doctors use these results to diagnose or monitor conditions like kidney disease, liver problems, or fluid imbalances. They may also check protein levels if you’re recovering from surgery or have symptoms like swelling or fatigue.

Common Conditions Affecting Results

Low protein levels might be linked to kidney failure, severe infections, or poor nutrition. High levels could result from dehydration, severe burns, or certain inflammatory diseases.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Plasma Protein Level

Frequently asked questions

What causes my protein levels to be unusually high or low?
High levels may be due to dehydration, severe burns, or conditions like multiple myeloma. Low levels can result from kidney disease, malnutrition, or chronic infections. Your doctor will discuss your specific situation.
Do I need to fast before this test?
Fasting may not always be required, but your doctor might specify if you should avoid food or drink for a few hours before your blood draw. Always follow their instructions.
How long will it take to get my results?
Results are typically available within a few days to a week, depending on your lab and healthcare provider. Your doctor will contact you once they’re ready for review.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy