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Protein Electrophoresis, Serum (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the different types of proteins in your blood serum using gel electrophoresis, a method that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma, liver disease, or kidney problems."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
6006-1
Short code
Prot C PPP Chro-aCnc
Synonyms
Prot C PPP Chro-aCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
chromo
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Proteins Are Being Tested?

Electrophoresis separates proteins into distinct bands, each corresponding to a specific protein group. Commonly identified bands include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal patterns may indicate conditions affecting protein production or breakdown.

Why Might This Test Be Ordered?

Your healthcare provider may order this test to diagnose or monitor conditions such as multiple myeloma (a cancer of plasma cells), chronic liver disease, kidney disease, or other disorders affecting protein synthesis or metabolism.

Sample Preparation and Testing Process

A blood sample is drawn, and serum is separated. The serum is then applied to a gel and subjected to an electric current, causing proteins to migrate based on their electrical charge and size. After separation, the gel is stained to visualize protein bands.

What Does an Abnormal Result Mean?

Abnormal results may show unusual bands, such as spikes (e.g., monoclonal spikes in multiple myeloma) or reduced levels of certain proteins. These findings can help guide further testing or treatment plans.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein Electrophoresis

Frequently asked questions

What does a protein electrophoresis test measure?
It measures the types, quantities, and distribution of proteins in your blood serum, helping identify potential abnormalities that may require further medical evaluation.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on the laboratory’s processing schedule and any follow-up tests needed.
Can I eat or drink anything before this test?
No special diet or preparation is required for this test. However, inform your healthcare provider about any medications or supplements you’re taking, as they may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy