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Protein Serum Electrophoresis (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the types and amounts of proteins in your blood serum using electrophoresis, a technique that separates proteins based on size and charge.

Quick summary

["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma or other blood disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
2858-9
Short code
Prot CSF/SerPl
Synonyms
Prot CSF/SerPl
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Electrophoresis separates proteins into distinct bands, each representing different protein groups (e.g., albumin, alpha-globulins, beta-globulins, gamma-globulins). This helps detect unusual protein distributions that may indicate underlying health issues.

Why It’s Done

Your healthcare provider may order this test to diagnose or monitor conditions such as multiple myeloma, lymphoma, or other blood disorders. It can also help evaluate kidney disease or other systemic conditions affecting protein levels.

Sample Collection

A blood sample is drawn from a vein, typically in your arm. The serum (liquid part of blood without clotting factors) is then separated and analyzed for protein composition.

Preparation & Results

No special preparation is needed, but fasting may be advised in some cases. Results are qualitative and focus on identifying abnormal protein patterns rather than specific numeric values.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Qual Serum Protein Electrophoresis

Frequently asked questions

What does a qualitative protein electrophoresis test show?
It shows the relative amounts and types of proteins in your serum, displayed as bands on an electrophoresis gel. Abnormal patterns (e.g., extra bands, missing bands, or spikes) may indicate conditions like blood cancers or kidney disease.
How long does it take to get results from this test?
Results are typically available within 24 to 48 hours, depending on lab processing times. Follow-up with your healthcare provider to discuss findings.
Can fasting affect this test?
Generally, fasting is not required for this test, but some labs may specify preparation instructions. Your provider will clarify if needed.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy