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24-Hour Urinary Protein Intake

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of protein excreted in your urine over a 24-hour period. It helps assess kidney function and detect conditions like proteinuria.

Quick summary

["This test tracks how much protein your kidneys filter and release in urine over a day."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
9084-5
Short code
Protein intake 12h
Synonyms
Protein intake 12h
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Measuring 24-hour urinary protein intake is critical for identifying kidney-related issues early. High protein excretion can signal kidney damage, chronic kidney disease, or other conditions affecting protein metabolism.

What to Expect Before the Test

You’ll collect all urine for 24 hours, typically starting after midnight. Drink plenty of water to ensure full collection, but avoid foods high in protein (like red meat) that day. Your healthcare provider will provide detailed instructions.

How the Test Works

Your urine sample is analyzed to quantify total protein excretion. The test measures the cumulative protein lost in urine, which may indicate kidney function or systemic conditions.

Common Conditions Monitored

This test helps diagnose or monitor conditions such as nephrotic syndrome, diabetic kidney disease, or glomerulonephritis, where protein leaks into urine excessively.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Elevated protein excretion may indicate impaired kidney function, inflammation, or metabolic disorders. Low levels may suggest dehydration or normal kidney function, but further evaluation is needed.

Short name

24h Urinary Protein Intake

Frequently asked questions

What does a high or low result mean?
A high result may signal kidney damage or disease, while a low result could mean normal excretion or dehydration. Your doctor will interpret results in context with your health history and other tests.
How often is this test repeated?
Your doctor may repeat this test if initial results are abnormal or to monitor progression of a known condition. Frequency depends on your diagnosis and treatment plan.
Can diet affect this test?
Yes, high-protein foods may increase protein excretion. Follow your provider’s instructions to avoid dietary changes that could skew results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy