Protein Electrophoresis (Serum/Plasma)
This test measures the distribution of different protein fractions in your blood, helping identify abnormalities in protein levels that may indicate conditions like kidney disease, liver problems, or certain cancers.
["Protein electrophoresis helps diagnose and monitor conditions affecting blood protein balance."]
Key facts at a glance
- LOINC
- 34539-7
- Short code
- Prot Elph Pnl Ur Elph
- Synonyms
- Prot Elph Pnl Ur Elph
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 7.35
- Ref high
- 7.45
- Critical range
- 7.2 N/A – 7.6 N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- electrophoresis
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Proteins Are Measured?
Electrophoresis separates blood proteins into groups based on size and electrical charge. Key protein bands include albumin, alpha-globulins, beta-globulins, and gamma-globulins. Abnormal patterns may signal underlying health issues.
Why Is This Test Done?
Your doctor may order this test to check for conditions like multiple myeloma, liver disease, kidney disease, or immune disorders. It can also help evaluate protein malnutrition or detect unusual protein fragments.
Sample Collection and Preparation
A blood sample is drawn from a vein, usually in your arm. The blood is then processed to separate serum or plasma for testing. No special preparation is needed, but fasting may be advised for some interpretations.
Interpreting Results
Results show the relative amounts of each protein group. A shift in bands (e.g., elevated gamma-globulins) may indicate immune system issues, while low albumin could signal liver or kidney problems. Your doctor will review results in context with your symptoms.
Reference range
NCBI: pH 7.35-7.45N/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein Electrophoresis
Frequently asked questions
What Does This Test Tell Us About My Health?
How Long Does It Take to Get Results?
Can I Eat or Drink Before This Test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy