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Protein-bound glucose concentration in plasma (24-hour urine collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of glucose (sugar) that is chemically bound to proteins in your urine over a 24-hour period. It helps assess how your body handles sugar over time, especially in people with diabetes or kidney issues.

Quick summary

["This test helps track long-term sugar control and kidney function in certain conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34546-2
Short code
Prot + Glucose Pnl CSF-mCnc
Synonyms
Prot + Glucose Pnl CSF-mCnc
Category
glucose
Sample
csf
Container
Sterile tube
Units
N/A
Ref low
70
Ref high
100
Critical range
50 N/A – 400 N/A
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
CPT
82947
SNOMED
260395008
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Matters

Protein-bound glucose is a specialized test that detects sugar molecules attached to proteins in urine. Unlike standard urine glucose tests, this method can reveal subtle sugar levels that might not appear in regular urine tests, helping doctors monitor kidney function and diabetes management more precisely.

What to Expect Before the Test

You’ll need to collect all urine for a full 24-hour period, typically starting after midnight and ending the next midnight. Drink plenty of water to help flush out your system. Follow your doctor’s instructions carefully to ensure accurate results.

How the Test Works

Your urine sample is analyzed to measure the concentration of glucose bound to proteins. The test uses a specialized method to detect these protein-bound sugars, which may indicate how well your kidneys are filtering glucose over time.

What the Results Mean

Higher-than-normal levels may suggest kidney problems, diabetes, or other metabolic conditions. Lower-than-normal levels might indicate poor kidney function or other underlying issues. Your doctor will interpret results in the context of your overall health.

Reference range

Fasting: 70-100 mg/dLN/A

Specimen: csf

Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Protein-bound glucose urine test

Frequently asked questions

How often should I get this test?
This test is usually ordered for people with diabetes, kidney disease, or those at high risk for metabolic disorders. Your doctor may recommend it periodically to monitor long-term sugar and kidney function. Follow their guidance for frequency.
What are the typical reference ranges?
Reference ranges vary by lab and individual health status. Your doctor will provide a personalized range based on your test results and medical history. Avoid relying on general ranges without professional interpretation.
Can I take medications before this test?
Yes, you may need to adjust or temporarily stop certain medications (like diuretics or blood pressure drugs) as directed by your doctor. Always ask before taking any medication on the day of your test.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy