Protein-bound Glucose (Serum/Plasma) Concentration
This test measures the amount of glucose chemically bound to proteins in your blood, often assessed in serum or plasma. It may be used to evaluate metabolic conditions or monitor glucose metabolism indirectly.
["This test helps assess how glucose interacts with proteins in your blood, useful in certain metabolic evaluations."]
Key facts at a glance
- LOINC
- 54246-4
- Short code
- Prot + Glucose Pnl Fld-mCnc
- Synonyms
- Prot + Glucose Pnl Fld-mCnc
- Category
- glucose
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 70
- Ref high
- 100
- Critical range
- 50 N/A – 400 N/A
- Fasting
- true
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82947
- SNOMED
- 260395008
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may order this test if they suspect conditions affecting how glucose is processed in your body, such as certain metabolic disorders, chronic kidney disease, or to monitor long-term glucose exposure in patients with diabetes or other conditions. It may also be part of a broader metabolic screening.
What to Expect During the Test
A blood sample will be drawn from a vein, typically in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The sample is then sent to a lab for analysis. No special preparation is usually needed, but always follow your provider’s instructions.
Sample Collection and Preparation
The test uses either serum (blood without clotting factors) or plasma (blood with clotting factors removed). The sample is analyzed to measure the concentration of glucose bound to proteins, which can be influenced by factors like hydration status, diet, or certain medications.
What the Results Mean
Interpreting results requires clinical correlation with your overall health and medical history. Elevated or altered levels may indicate underlying metabolic issues, but results alone cannot diagnose a condition. Your healthcare provider will discuss findings with you in the context of your symptoms and other tests.
Reference range
Fasting: 70-100 mg/dLN/A
Fasting for 8-12 hours required. Water is permitted. Avoid chewing gum and smoking before the test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Protein-bound glucose
Frequently asked questions
What could cause abnormal results?
How often should I get this test?
Can I prepare for this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy