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Protein Pattern Urine Immunofixation

Published: August 9, 2026Updated: August 16, 2026

This test helps identify specific types of proteins in your urine that may indicate conditions like multiple myeloma, amyloidosis, or other protein-related disorders.

Quick summary

["Detects abnormal urine proteins to guide diagnosis of serious conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
14896-5
Short code
Prot Pattern Ur IFE-Imp
Synonyms
Prot Pattern Ur IFE-Imp
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immunofixation
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you have symptoms like frequent urination, unexplained weight loss, fatigue, or if lab results show unusual protein levels in your urine. It’s also used to monitor known conditions affecting protein production or excretion.

How the Test Works

A small sample of your urine is collected and analyzed using an immunoassay technique. This method separates proteins into distinct bands, allowing for precise identification of specific proteins, including monoclonal spikes (common in multiple myeloma).

What to Expect Before the Test

No special preparation is needed. You may drink plenty of water the day of the test to ensure a good urine sample, but avoid excessive protein-rich foods or medications that could interfere with results.

What to Expect During the Test

You’ll provide a urine sample, typically collected in a clean container. The lab technician will handle the sample carefully to preserve protein integrity for accurate testing.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Urine Immunofixation Protein Profile

Frequently asked questions

What does a positive result mean?
A positive result may indicate an underlying condition affecting protein production or excretion, such as multiple myeloma or other plasma cell disorders. Follow-up testing and evaluation by a healthcare provider are necessary to determine the cause.
How often should I get this test?
Your healthcare provider will determine the frequency based on your symptoms, medical history, and test results. Some patients may need monitoring every few months or annually, depending on their condition.
Can diet or medications affect this test?
Certain medications (e.g., some diuretics, chemotherapy drugs) or dietary changes (e.g., high-protein diets) may influence urine protein levels. Always inform your provider about all medications or supplements you’re taking.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy