Protein Electrophoresis with Free Albumin and Alpha-1 Antitrypsin Quantification

Why This Test Is Done

Your healthcare provider may order this test to evaluate conditions affecting protein metabolism, such as liver disease, kidney problems, or inherited protein disorders. It can also help diagnose or monitor conditions like alpha-1 antitrypsin deficiency, which can lead to lung or liver issues over time.

What to Expect Before the Test

No special preparation is needed. You’ll typically have a small needle inserted into a vein in your arm, and blood will be drawn into a test tube. If you’re nervous, let your provider know—they can offer comfort measures.

What the Test Results Mean

The test separates proteins by size and charge, showing patterns of albumin, alpha-1 antitrypsin, and other proteins. Free albumin and alpha-1 antitrypsin levels are quantified separately. Abnormal patterns may indicate conditions like liver disease, protein loss, or genetic disorders.

Common Conditions Monitored

This test is often used to monitor alpha-1 antitrypsin deficiency, a genetic disorder causing lung or liver damage. It may also help diagnose or track conditions like nephrotic syndrome (kidney disease causing protein loss) or chronic liver disease.