Protein Electrophoresis, Serum (Qualitative)
This test measures the different types of proteins in your blood serum using electrophoresis, a technique that separates proteins based on size and charge.
["Helps identify abnormal protein patterns that may signal conditions like multiple myeloma or other blood disorders."]
Key facts at a glance
- LOINC
- 72337-9
- Short code
- Prot S Ag PPP IA-aCnc
- Synonyms
- Prot S Ag PPP IA-aCnc
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- ia
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
Electrophoresis separates proteins into distinct bands based on their electrical charge and molecular weight. The test detects variations in protein composition, such as abnormal spikes or bands that may indicate conditions affecting protein production or breakdown.
Common Uses
This test is often used to diagnose or monitor conditions like multiple myeloma, Waldenström macroglobulinemia, or other plasma cell disorders. It may also help evaluate kidney disease or liver disorders that affect protein synthesis.
How the Test Works
A small blood sample is drawn and mixed with a special solution. An electric current is applied, causing proteins to migrate through a gel matrix. After separation, the gel is stained to visualize protein bands, which are then analyzed for abnormalities.
Preparation
No special preparation is typically needed, but you may be asked to avoid certain medications or supplements that could interfere with results. Fasted or non-fasted status may not affect this test.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Abnormal protein patterns, such as a monoclonal spike (Bence Jones proteins) or altered albumin/globulin ratios, can indicate underlying conditions like plasma cell dyscrasias, liver disease, or kidney problems. This test is critical for early detection and management of certain blood disorders.
Short name
Protein Electrophoresis
Frequently asked questions
What causes abnormal protein patterns in this test?
How long does it take to get results?
Can diet or medications affect this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy