: Protein, Serum or Plasma, Mass Concentration Measurement
: This test measures the total amount of protein in a sample of serum or plasma, helping give a general picture of your nutritional and fluid status.
[": A serum protein measurement is a general indicator of overall protein balance in the body."]
Key facts at a glance
- LOINC
- 2884-5
- Short code
- Prot Smn-mCnc
- Synonyms
- Prot Smn-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
: What This Test Measures
: Your blood contains many different proteins that perform jobs like carrying nutrients, fighting infection, and maintaining fluid balance. This test measures the combined mass of all these proteins in the liquid part of your blood (serum or plasma) and reports it as a mass concentration.
: Why It Is Ordered
: A clinician may order this test as part of a general health panel or when monitoring conditions that affect protein levels, such as liver or kidney problems, nutritional concerns, or unusual swelling. It is often interpreted alongside other tests such as albumin.
: How the Sample Is Collected
: A small blood sample is drawn from a vein, usually in your arm. Serum or plasma is then separated from the blood cells in the laboratory so the protein can be measured. No special preparation is typically needed unless your clinician says otherwise.
: Understanding Your Results
: Results are reported as a concentration, but a single value is rarely interpreted alone. Your clinician considers the result together with your symptoms, other lab tests, and your overall health. If your level is outside the expected range, they may recommend additional testing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
: Serum Protein
Frequently asked questions
: Do I need to fast before this test?
: What can cause an abnormal protein level?
: Is this the same as an albumin test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy