Protein Electrophoresis with Serum/Plasma Mass Concentration Quantification (Qualitative/Quantitative)

What Proteins Does This Test Measure?

Electrophoresis separates blood proteins into fractions based on their electrical charge and size. Commonly detected proteins include albumin, globulins (such as immunoglobulins), and other smaller or larger proteins. Abnormal bands or patterns may indicate conditions like infections, autoimmune diseases, or genetic disorders.

Why Might You Need This Test?

Your doctor may order this test to diagnose or monitor conditions such as multiple myeloma, liver disease, kidney disease, or certain types of immune disorders. It can also help assess protein loss in urine (proteinuria) or evaluate protein synthesis issues.

How Is the Test Performed?

A blood sample is drawn, typically from a vein in your arm. The serum or plasma is then placed in an electric field to separate proteins by size and charge. A gel or paper strip shows bands representing different protein types, which are analyzed for concentration and pattern.

What Are Common Findings?

Normal results show distinct bands with expected protein distributions. Abnormal findings may include extra bands (e.g., monoclonal spikes), missing bands, or altered patterns. These changes can signal underlying health issues requiring further testing or treatment.